Rabbit anti Human CD234 (N-Terminal) Bio-RadCD234抗体 AHP1708-产品中心-Avidity官网瑞孚迪Revvity和PerkinElmer珀金埃尔默，revvity瑞孚迪 (Revvity)为生命科学和诊断业务公司

Rabbit anti Human CD234 (N-Terminal) Bio-RadCD234抗体 AHP1708

2024-10-22

Rabbit anti Human CD234 (N-Terminal)

货号：AHP1708

规格：0.1 mg

市场价格：5160

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CD234

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human CD234 antibodydetects CD234, also known as DARC, a multi-pass membrane protein belonging to the G protein coupled Duffy family. CD234 is a non-specific receptor for a number of cytokines including IL-8, GRO, RANTES, MCP-1 and TARC.CD234 also functions as the receptor for the malaria parasites Plasmodium vivax and P. knowlesi. CD234 is also responsible for the Duffy blood group system where a substitution at position 42 of either Gly-42 or Asp-42 results in Fy(A) or Fy(B).CD234 is present in adult kidney, adult spleen, bone marrow and fetal liver. In particular, it is expressed along post capillary venules throughout the body, except in the adult liver. Erythroid cells and post capillary venule endothelium are the principle tissues expressing duffy. Fy(-A-B) individuals do not express duffy in the bone marrow, however they do, in postcapillary venule endothelium. It has been demonstrated that CD234 exists in multiple isoforms.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
AntiserumPreparation	Antisera to Human CD234 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02% Sodium Azide (NaN₃)
Immunogen	A peptide corresponding to a 18 amino acid sequence from near the amino terminus of Human CD234.
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Immunohistology - Paraffin¹	√		5.0ug/ml
Western Blotting	√	1.0	2.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.¹This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. Histology Positive Control Tissue Human brain tissue Western Blotting AHP1708 detects a band of approximately 16kDa in PC-3 cell lysate
相关产品
Description	Product Code	Applications	Pack Size
Antigen Retrieval Buffer, pH8.0	BUF025A	P	500 ml
TidyBlot Western Blot Detection Reagent:HRP	STAR209P	WB*	0.5 ml
文献
1.Gardner, L.et al.(2004) The human Duffy antigen binds selected inflammatory but not homeostatic chemokines.Biochem Biophys Res Commun. 321 (2): 306-12.2.Chaudhuri, A.et al.(1993) Cloning of glycoprotein D cDNA, which encodes the major subunit of the Duffy blood group system and the receptor for thePlasmodium vivaxmalaria parasite.Proc Natl Acad Sci U S A. 90 (22): 10793-7.3.Gil, M.L.et al.(1992) A member of the tetra spans transmembrane protein superfamily is recognized by a monoclonal antibody raised against an HLA class I-deficient, lymphokine-activated killer-susceptible, B lymphocyte line. Cloning and preliminary functional studies.J Immunol. 148 (9): 2826-33.

技术参数

产品应用 P* ;WB

产品类型 Polyclonal Antibody

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