Animal-Free Recombinant Human Flt3-Ligand
货号：AF-300-19-10,AF-300-19-100,AF-300-19-1000,AF-300-19-2,AF-300-19-250,AF-300-19-50,AF-300-19-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
市场价格：2830,16550,66220,1250,28960,9930,43040
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant Human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues.Manufactured using all Animal-Free reagents.来源:E.coli别名:Fms-related tyrosine kinase 3 ligand, Flt3L氨基酸序列:TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the dose-dependent stimulation of the proliferation of human AML5 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106units/mg.Calculated Molecular Weight:17.6 kDaAccession Number:P49771Gene ID:2322交叉反应:Human,Human + Hamster,Monkey,Mouse,Rabbit |
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